Disinfection 2010 & Sterilization  Hospitals "MVX"

MVX Fighting H5N1 Bird Flu ( avian flu )

• Nanotechnology & Sterilization 

• Nosocomial Infection .

• Titanium dioxide TiO2

• What is photo catalyst  TiO2

• Mechanism of action  " MVX " for Sterilization

• Functions of Sterilization " MVX "

• MVX " Antiviral effect ( avian flu )

• MVX Anti Fungal Effect

• MVX Anti Dirt Effect

• Quality & Safety

Nanotechnology and Sterilization of hospitals

It's the revolutionary science and art of manipulating matter at the atomic
 or molecular scale. The objective of nanotechnology is to produce
materials of special function with new physical & chemical properties
by making atoms & molecules behave differently.

Nanotechnology is considered to be one of the most important sites of investment funded by the governorates, and here are some examples for the fund of pioneers in nanotechnology.

Nanotechnology was our gate to reach a new material; it's old in reality but with this new technology we have changed lots of its properties; it's titanium dioxide TiO2

Nosocomial Infection

Although Nosocomial infections have been recognized since more over than 150 years but they remain a hazard to both health workers & patients.  Infection control has become a formal discipline in the United States since the 1950s due to the spread of staphylococcal infections in hospitals. Today Nosocomial infections accounts for 50% of all major complications of hospitalization. In 1974 only 2% of staphylococcus aurous infections can't be cured with commonly used antibiotics. By 2003, that figure had reached 57% and is still rising. The cause is that microbes existing in environment where antibiotics are constantly used are likely to develop a resistance to most of these antibiotics in use

And stated sites of infection are:
So, we are facing a real problem which is that disinfection systems can't meet the recommended degree of disinfection by far especially in the developing countries. And that's why Japanese scientists don't stop studies for reaching solutions for the problem especially with the introduction of nanotechnology Nanotechnology & Sterilization

Titanium dioxide TIO2

TiO2 is a white powder, used extensively in many commercial products including paints, plastics, paper, food & cosmetic products. TiO2 is insoluble in water & sensitive as a photo catalyst to certain wave length of ultraviolet light, nanotechnology had changed its characteristics, dissolved it in water & made it sensitive to any source of light. So it can be used as a photo catalyst when exposed to any source of light.

What is photo catalyst ?

It is a material which is sensitive to light excited and makes a chemical reaction when light strikes it. For example, chlorophyll in green plants is a photo catalytic material begins a chemical reaction when exposed to light.

TiO2 photo catalysis

Our new titanium dioxide " MVX " when stroked by light a chemical reaction will begin causing the breakdown of organic toxins, odors & moreover.

Mechanism of action for " MVX " Sterilization

(A) At the level of radicals

When light strikes "MVX" this produces two oxidation reactants, hydroxyl radicals (OH-) & super oxide anion (O2-). The two reactants decompose toxic organic substances through oxidation. The light source only begins the reaction & it keeps working for several hours even after the light source is cut

(B) At the level of molecules:

The nucleus of an atom is surrounded by orbits where electrons are revolving around the nucleus. Electrons responsible for reactions are revolving in a band called valence band.

There is a band outside the valence band referred to as the conduction band.

In TiO2, as it is a compound consisting of different atoms, the valence and conduction bands are complicated, but the principles involved are the same. When the energy of light is applied externally electrons in the valence band are excited and rise to the conduction band. Then positive holes are formed and left behind the rising electrons in the valence band. At this time the MVX is photo excited. The resulting positive holes show sufficient oxidative power.

As MVX is TiO2 dissolved in water, water is oxidized by positive holes forming hydroxyl radicals (OH-) which has a strong oxidative decomposing power.

Also, Oxygen of the air is reduced by the rising electrons resulting in the production of super oxide anions (O2-) which is capable of attacking bacteria. Both super oxide anion and hydroxyl radicals are the main reactants responsible for the functions of MVX.

Functions of Sterilization " MVX "

1) Antibacterial & Detoxification Action

MVX has excellent bactericidal effects even without ultra violet rays, furthermore, when U.V. rays are irradiated,  MVX also can decompose the remnants of dead bacteria.

(A)Test Results

(B)MIC Minimum Inhibitory Concentration

The antibacterial Performance standard established by the society of industrial technology for antimicrobial articles (SIAA) in Japan is 800 µgm/ml or less, MVX is certified to have an antibacterial effect, the measured MIC values for different types of bacteria shown in the table.

Testing organizations
1- Microbiology laboratory, Faculty of pharmacy, Meijo university in Japan.
2- Japan food Research laboratories.

MVX Antiviral effect avian flu

MVX has strong effect on killing almost all kinds of viruses including SARS & Avian flu ( H5N1 ).

Effect against influenza viruses

The amount of antibodies in normal blood uninfected by viruses is approximately 2 µgm/ml which was   defined as HA value = 2, when blood is infected by a virus, hem agglutinin occurs, causing antibodies to increase in number. The HA value of 1280 for the untreated samples means that the virus caused heamgglutination and increased the number of antibodies by 640 times.

-On the other hand, the samples treated with the MVX inhibited heamagglutination by destroying the virus.

N.B the numerical values are HA values (n=3) measured after 24 hours of contact.
(#) Mark: indicates that hem agglutination was not observed.
Sample virus: influenza virus AOPR8
Testing organization: Kitasato Research center of environmental sciences.

MVX  Anti Fungal Effect

MVX has a good antifungal effect on different types of fungi e.g. Aspergillums Niger & Candida albicans reducing their concentration by 34.65% after 2 hours of contact.

MVX Deodorizing Effect

MVX produces a noticeable difference in deodorizing character. The smell of very high concentrations of ammonia gases (40 ppm) in a 2 hour period will dissipate up to 99.6%.

MVX Anti Dirt Effect

MVX gives relative charges to the surface it's coated with when exposed to every source of light, also fine dust carries negative charges so, both the surface & the dust carry negative charge and they repel with each other so, surface clear without accumulation of dust.

MVX Hydrophilic effect

M character due to the presence of (OH-) radicals, with very high affinity to water, and self cleaning effect is generated by waterfall.

THE ACTIVITY OF " MVX  "

MVX produces long lasting disinfection remains for 5 years and certainly we have a very good visible proof for the validity of MVX functions as a sterilizing material for surfaces. As we have known that the mechanism of action of MVX depends on the presence of (OH-) & (O2-) radicals.

So, we have 2 tests ensuring the presence of these two radicals.

(1) Silver nitrate : is a colorless solution turns black in color due to the presence of O2- radicals .
(2) Methelene blue : is a blue colored liquid when oxidized, its color fades within 30 minutes due to the presence of (OH-) radicals.

At the start of the test	After 30 minutes	After 90 minutes

Mold resistance test
( 1 ) Aspergillus niger
                 Black yeast mold – drying matrix; fiber, industrial product.
( 2 ) Penicillium citrinum
                 Blue mold – resistant to drying; propagates in general houses.
( 3 ) Rhizopus oryzae
                Spider web mold ( Kumonosu kabi ) general foods.
( 4 ) Cladosporium / cladosporioides
         Black scale mold ( Kurokawa kabi ) – propagates in humid places such as a bathroom and washroom
( 5 ) Chaetomium globosum
               “ Ketana kabi “ mold – resistant to coldness; propagates on silk, jute and paper

1.What is titanium dioxide? What is a photo catalyst ?

Titanium dioxide (TiO2) is an anti-microbial metal created by a process which crystallizes titanic iron ore

into a nano liquid form. When exposed to normal light, TiO2 becomes a photo catalyst

oxidizer (PCO) as well which creates hydroxyl radicals and superoxide ions which are two times stronger disinfectants than chlorine and 1.5 times stronger a disinfectant than ozone. TiO2 is safe and widely used in many household products such as toothpaste, food, and teeth whitening solutions

The advent of nanotechnology, in other words making tiny particles out of metals that can penetrate most surfaces,
has lead to several Japanese patents utilizing this nano TiO-2 photo catalytic solution which has many wide ranging applications and has experienced years of successful use in the Japanese marketplace

For instance the government uses this solution in some public bathrooms to keep them smelling fresh and more importantly maintenance free. TiO2 coatings are applied to some highway guard rails to keep them looking new amidst constant bombardment from hydrocarbons and VOC's from vehicle exhaust

The outside of some Japanese high rises are treated with TiO2 solution to make the glass and metal maintenance free, no more need to clean the windows, they resist water and grime. TiO2 coatings are also widely used in the healthcare, food, janitorial, auto, and construction business. Many homeowners treat their mini-blinds, windows, furniture, bathrooms, showers, carpets, flooring, etc with similar TiO2 solutions to reap the benefits of VOC free, clean, fresh indoor air on top of the huge benefit of maintenance free surfaces. When microorganisms, smog, viruses, VOC, or any organic material comes in contact with the TiO2 treated surface, it also becomes oxidized. Even fabrics treated with this revolutionary substance will not retain odors. Car interiors treated with Nano TiO2, even when submitted to second hand smoke from several people for prolonged periods of time, will not retain any tobacco
odor.

2. Are TiO2 coating harmless to humans? Is it harmless to pets ?

Nano TiO2 liquid is completely harmless to human bodies and is actually used widely as a food additive. View test results) Nano TiO2 liquid is made with a patented binding process that makes it possible for(
this liquid to penetrate and form a permanent bond with surfaces. It is not for human consumption in this nano liquid form of course. However, after it dries to form a film on a substance, it becomes one with the surface. Nano TiO2 liquid should not be applied directly on pets or animals. It can and should be used however to keep pet bedding from retaining odors

3. After applied, does it produce any odor ?

No, it does not have any odor. If applied to surfaces with for instance tobacco odors, those odors will go
away.

4. Does this Nano TiO2 liquid have a shelf life ?

Basically, there is no shelf life . This solution should be stored in a dark, cool environment long term
however.

5. How is this Nano TiO2 liquid applied ?

It can be brushed or sprayed onto surfaces. When applied to fabrics via spray, a brush should be used
to work the solution into the fabric.

6. After it is applied, how long does it last ?

The Titanium crystals in Nano TiO2 liquid form bonds that are semi-permanent. In case of some
materials that may undergo a physical peeling off by some force (such as carpets, mats, and clothing), it
is recommended to reapply the solution every 3 years. Generally speaking TiO-2 PCO Solution has a
service life of 5-10 years or even longer on some surfaces that do not have a lot of contact. Basically,
our solution will out-live many materials such as curtains, carpets, shingles, etc.

7. Does Nano TiO2 liquid cause any fabric discoloration or any streaking effects on solid surfaces?

Nano TiO2 liquid can be applied to fabrics, curtains, carpets, woods, tiles, ceramics, glass, even metal
and painted surfaces. If the surface is exposed to direct sunlight, do not apply to black or very dark
colored surfaces as the oxidation process can remove some pigments from surfaces. Indoor light is not
strong enough to cause this oxidative reaction on fabrics and surfaces however. When spraying any
surface with Nano TiO2 liquid, it is always advisable to spray a small area first (test area) then allow to
dry to make sure the solution does not react with the surface. Do not apply Nano TiO2 liquid to leather,
silk, or fine garments. Once you are confident that the fabric or material can safely be treated, spray the
surface until it is completely moistened then brush in with any type of brush to work the Nano TiO2 liquid
into the fabric. If applied to non fabric surfaces (plastic, metal, glass, etc) the initial coat will leave a fine
milky residue. Allow the area to completely dry then wait several hours and wipe the area with a damp
cloth.

8. How long does it take it to dry?

A film will have formed once the liquid has completely disappeared. The time needed for this to occur
(evaporation time) will be varies with temperature, wind, and film thickness. Generally speaking, it only
takes 5-15 minutes to dry on solid surfaces and around 1 hour or longer to dry on fabrics. Use a blow
dryer to speed up the drying process as well as aid with the bonding process.

9. How long does Nano TiO2 liquid have be exposed to light before it released oxidizers into the air to get rid of indoor air pollution?

Studies have shown that this Nano TiO2 liquid will actively begin creating hydroxyl radicals and
superoxide ions when exposed to ultraviolet rays in the sub 400nm range. Regular house lights will even
activate the TiO2's disinfectant effect to a minor extent, especially florescent type lamps such as those
found in many kitchens. However it's direct sunlight, UV radiation, and black lights (UVA) that create the
most oxidizers Hydroxyl radicals and superoxide ions do not give off a strong beech like ozone does but
they do aggressively go after odors and air pollution better than ozone or chlorine.

10. Does Nano TiO2 liquid remove odors from the air? From fabrics?

The surface area of titanium dioxide per gram is about 300um (equivalent to that of activated charcoal).
When exposed to light, Nano TiO2 liquid will create -OH (hydroxyl radical) and O- (super oxide ions)
which will decompose the substances which are creating the odor. The principal difference between
titanium dioxide and other odor adsorbing substances including activated carbons is that titanium
dioxide will repeats this disinfectant function semi-permanently vs. activated carbon and other adsorbing
substances such as Zeolite which lose their effectiveness once they're full of absorbed substances.

11.How does Nano TiO2 liquid prevent and remove contamination from surfaces?

The reason why airborne contaminants such as second hand smoke, car exhaust, molds, VOC's,
viruses, bacteria, etc cannot adhere to surfaces treated with Nano TiO2 liquid is that they become
oxidized by the photo-catalytic oxidation and float away as harmless substances.

12. Why does Nano TiO2 liquid have a sterilizing and anti-microbial effect?

The old standard for killing airborne microorganisms has been strong UVC radiation. (Over 20,000
microwatt's of UVGI per second) UVC germicidal radiation kills microbes by destroying their DNA.
However, some microorganism, anthrax most notably, have very strong DNA coatings and can resist
even 30,000 microwatt's of UVGI. Our Nano TiO2 liquid works in a different way. Titanium dioxide
decomposes and destroys the cell membrane, not the DNA. Most microbes are single celled organisms
so they die quickly when any part of them comes in contact with a coated surface. Accordingly, titanium
dioxide even kills MRSA (Staphylococcus Aureus) a major cause of hospital infections. Our TiO2
solution has also been proven to even kill other types of microbes that are not even killed by antibiotics!
(TiO2 is not selective on types of microorganism it kills, it kills them all). For this reason, Japanese
hospitals have shown great anti-bacterial results with our particular patented brand of TiO2 solution. In
addition, our Nano TiO2 liquid decomposes toxins that are discharged when microbes die (Verotoxins,
Enterotoxins), rendering them into harmless vapors.

13. Exactly what types of odors will Nano TiO2 liquid eliminate?

It will remove virtually all and any type of odor from surfaces as treated surfaces become resistant to
microorganisms, mold, bacteria, viruses, smoke, odors, etc. It removes odors from the air when a treated
surface is exposed to certain light thus creating the photo catalytic oxidative superoxide ion and hydroxyl
effect.

14. Does it work in cold environments such as freezers?

Yes. Microbes that come in contact with a treated surface will cease to exist.

15. Does Nano TiO2 liquid get rid of cigarette odors from tar and nicotine that have penetrated surfaces?

Yes. If a second hand smoke contaminated surface (second hand smoke is known to have over 400
known cancer causing chemicals) is treated with TiO2 PCO Solution, the odor will soon disappear.
However, the discoloration caused by second hand smoke does not disappear. It is therefore advisable
to first wash smoke contaminated surfaces that show discoloration before treatment.

16. How does the intensity of light effect the ability of this Nano TiO2 liquid to create friendly oxidizers which purify the air?

As a characteristic of titanium dioxide, it starts to produce friendly oxidizer en mass when exposed to
ultraviolet rays of 400nm range or lower. It is more affected by the intensity of the ultraviolet rays rather
than the intensity of light itself per se. However, any air pollution, VOC, or odor that comes in contact
with a surface treated with Nano TiO2 liquid will become oxidized.

17. What are some of the more popular applications for Nano TiO2 liquid?

Bathrooms, floor tiles, sinks, showers, car interiors, to remove and prevent tobacco odors, kitchen
counters, furniture and carpets (especially if you have pets), curtains, mini-blinds, windows exposed to
light, ceiling fans, car rims, white outdoor furniture, house gutters (keep them mold free), concrete or
brick that you want to keep mold free, the list goes on and on.

18. Can Nano TiO2 be applied to carpets?

Yes, and with great results! Carpets treated with Nano TiO2 will resist not only odors and grime but also
pests such as fleas. Carpets will last much longer as well. For this reason, carpets and fabrics in trains
and pubic transportation are now being treated with Nano TiO2 in Japan with great results.

Quality Compatible with photo catalyst performance evaluation test.		Acquired the SITPA mark of the society of industrial technology for photo catalytic articles. Certification society: the photo catalytic product technology council the certificate has been acquired in march 2002
Safety : 1- Acute toxicity test. 2- Skin irritation test. 3- Mutagen city test. 4- Sensitization test.	No abnormality was observed in all Japan food research laboratories	The SITPA mark is a mark to be put on products of which quality management is carried out in accordance with the "autonomous standards for quality and safety" and "guidelines on photo catalytic products" prepared by the society of industrial technology for photo catalytic articles.
MVX : 1- Broad spectrum sterilization , no target selection . 2- High performance and everlasting effect . 3- decomposition of germ body and end toxin . 4- Safety, no extra pollution, environment friendly and harmless to human being . Certificated " MVX " Sterilization & Disinfections   to view our certificated from Japan click her >>           for more certificated Download now